The Society for Biological Therapy was founded in 1984 with 40 charter members. The Society currently has over 400 members consisting primarily of MDs, PhDs, RNs, and corporate representatives. Scientific and business meetings have been held annually since the first Annual Meeting of SBT in 1986. At the 2002 business meeting held November 9, 2002, the SBT membership voted to officially change the name of the Society and it thus became the International Society for Biological Therapy of Cancer (iSBTc).

Recent advances in immunology and biology have opened up new horizons in the field of cancer therapy, with an upsurge in the integration of new biologic agents into clinical practice. The goals of the International Society for Biological Therapy of Cancer for 2003 are directed towards the rapid dissemination of information in these areas to expedite the safe transfer of both basic and applied research to the clinical setting.