Program Schedule

Saturday, November 9, 2002
7:00 am-6:00 pm Registration Open
7:00 am-8:00 am Continental Breakfast in the Exhibit Hall
8:00 am-8:05 am Keynote Address Introduction
Robert O. Dillman, MD
Hoag Cancer Center
8:05 am-9:00 am Keynote Address
Targeting Genes to the Neovasculature
David A. Cheresh, PhD
The Scripps Research Institute
9:00 am-9:15 am Refreshment Break
9:15 am-11:30 am Joint Session: Angiogenesis
Co-Chairs:
Lee Ellis, MD
MD Anderson Cancer Center
Lee S. Rosen, MD
Cancer Institute Medical Group
9:15 am-9:45 am Antiangiogenic Metronomic Chemotherapy: Preclinical and Clinical Aspects
Robert Kerbel, PhD
Sunnybrook Health Science Center
9:45 am-10:15 am Lee M. Ellis, MD
MD Anderson Cancer Center
10:15 am-10:45 am Lee S. Rosen, MD
Cancer Institute Medical Group
10:45 am-11:00 am Requisite Role of p38 MAPK in Mural Cell during Angiogenesis
Wen-Hui Zhu, MD, PhD
University of Washington
11:00 am-11:15 am Therapeutic Effects of Anti-flt-1 and Anti-kdr Ribozymes Against Primary & Metastatic 4T1 Murine Mammary Carcinoma
Julian A. Kim, MD
The Cleveland Clinic Foundation
11:15 am-11:30 am Functional CT Measurement of Tumor Angiogenesis
Satoshi Kobayashi, MD
MD Anderson Cancer Center
11:30 am-1:00 pm Poster Session (authors must be present)
Box lunches will be available in the Scripps Hallway
1:00 pm-2:30 pm Presidential Session
Sponsored by a grant from
Chair: Robert O. Dillman, MD
Hoag Cancer Center
1:00 pm-1:15 pm Differential Cytokine Expression by Mature and Immature Dendritic Cells
Dirk Nagorsen, MD
National Institutes of Health
1:15 pm-1:30 pm Changes in Plasma Levels of Pro-Angiogenic Factors in Patients Receiving Interleukin-12 and Interferon-alpha
Jennifer Biber
Ohio State University
1:30 pm-1:45 pm Fixed Tumor Cell Vaccines Containing a Cytokine-Slow-Release Material-Effects on Mouse Lung, Hepatocyte, and Ovarian Carcinoma Model
Eiji Uchimura, PhD
RIKEN Cell Bank
1:45 pm-2:00 pm Vaccine-Based Therapy Directed Against a Self Antigen (CEA) Demonstrates Anti-Tumor Activity of Spontaneous Colorectal Tumors in the Absence of Autoimmuntiy In CEA.Tg/ MIN Mice
Hasan E. Zeytin, MD PhD
National Cancer Institute, NIH
2:00 pm-2:15 pm Induction of IFN-G Producing Cells Recognising Ep-CAM Derived MHC Class I Restricted Peptides after Immunisation with a Recombinant Ep-CAM Protein or a Human Anti-Idiotypic Antibody Mimicking Ep-CAM
Szilvia Mosolits, MD
Cancer Center Karolinska
2:15 pm-2:30 pm Peptide Targeting of Interleukin-12 to Neovasculature Reduces Its Toxicity
Erin B. Dickerson, PhD
University of Wisconsin
2:30 pm-2:45 pm Refreshment Break
2:45 pm-5:00 pm Concurrent Session 1: Cytokines
Co-Chairs:
Michael T. Lotze, MD

University of Pittsburgh
Jeffrey A. Sosman, MD
Vanderbilt University
2:45 pm-3:15 pm Efficient TH1 Response Depends on Coordinate Action of IL-12, IL-13 and IL-27
Stefan Pflanz, PhD
DNAX Research Institute
3:15 pm-3:45 pm DC-Activating Function of the IL-1 Homologues [IL-1, IL-18, IL-1F7] and NK Cells in the Development of Antitumor Responses
Michael T. Lotze, MD
University of Pittsburgh
3:45 pm-4:15 pm Cytokine Deregulation in Cancer
Razelle Kurzrock, MD
MD Anderson Cancer Center
4:15 pm-4:30 pm A 3-Arm Randomized Comparison of High and Low Dose Intravenous and Subcutaneous Interleukin-2 in the Treatment of Metastatic Renal Cancer
James C. Yang, MD
National Cancer Institute, NIH
4:30 pm-4:45 pm Mechanisms of Enhanced Antigen-Specific T Cell Response Following Vaccination with a Novel Peptide-Based Cancer Vaccine and Systemic Interleukin-2
Mohamed Salem, PhD
Medical University of South Carolina
4:45 pm-5:00 pm Systemic Administration of IL-15 Augments the Antigen-Specific Primary CD8+ T Cell Response Following Vaccination
Mark P. Rubinstein
Medical University of South Carolina
2:45 pm-5:00 pm Concurrent Session 2: 2001 Immune Monitoring Workshop Follow-Up
Co-Chairs:
Jeffrey S. Weber, MD, PhD
Norris Cancer CenterUlrich Keilholz, MD
University Hospital Benjamin Franklin
2:45 pm-3:15 pm Mary L. (Nora) Disis, MD
University of Washington
3:15 pm-3:45 pm HLA Antigen Abnormalities in Malignant Cells
Soldano Ferrone, MD, PhD
Roswell Park Cancer Institute
3:45 pm-4:15 pm Lessons from Immune Monitoring of Clinical Trials
Carmen Scheibenbogen, MD
University Hospital Benjamin Franklin
4:15 pm-4:30 pm Quantitating Antigen-Specific T Cell Responses in Peripheral Blood- A Comparison of Peptide MHC Tetramer, ELISpot and Intracellular Cytokine Analysis
Timothy Clay, PhD
Duke University Medical Center
4:30 pm-4:45 pm Migratory Pattern of Cytotoxic T Cells: Melanoma-Reactive CD8+ Effector T cells Express CXCR4 and Accumulate in Bone Marrow
Anne Letsch, MD
University Hospital Benjamin Franklin
4:45 pm-5:00 pm Hallmarks of Effective Immunity: Avidity and Homing of Tumor-Specific T-Cells
Markus Maeurer, MD
University of Mainz
5:00 pm-6:30 pm
Presidential Reception
Announcement of Presidential Award Winner